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Breast cancer is the most common cancer among women, except for nonmelanoma skin cancers. The chance of developing invasive breast cancer at some time in a woman's life is about 1 in 8 (13% of women). It is estimated that in 2005 about 211,240 new cases of invasive breast cancer will be diagnosed among women in the United States. At this time there are slightly over 2 million breast cancer survivors in the United States. Women living in North America have the highest rate of breast cancer in the world.

Breast cancer is the second leading cause of cancer death in women, exceeded only by lung cancer. The chance that breast cancer will be responsible for a woman’s death is about 1 in 33 (3%). In 2005, about 40,110 women and 470 men will die from breast cancer in the United States. Death rates from breast cancer have been declining. These decreases are believed to be the result of early detection and improved treatment.